Objectives: The main purpose of this study was to investigate the prevalence and the reasons for permanent teeth extractions in Split. The specific aims of this study were to assess whether the reasons for extraction were different for people of different gender, age and different social groups and to determine whether the frequency of visits to the general dentist affects the need for extraction and for what reasons. Materials and methods: This research has been carried out in a clinic for oral surgery in a hospital centre in Split. The data was collected in the period from April 18th to May 18th, 2018. For the purposes of this study, a table was made containing the basic demographic characteristics of patients such as age, gender, occupation and frequency of visits to their general dentist. In the second part of the table, the labeling of the extraction teeth (dual system) and the reason for extraction (caries, periodontitis, endodontic reasons, impacted third molar and orthodontic reasons) were entered. The decision for extraction was based on a clinical examination and X-ray analysis. There were 155 patients that participated in this study, of which 52.3% were women and 47.7% men. Results: The most common reason for tooth extraction was caries. Out of 155 extractions, 100 were performed due to caries (64.5%). The largest number of extraction was performed in the age group of 18 to 35 years, and caries was the leading cause of extraction in all age groups. No statistically significant differences were found between men and women in the number of extractions. Regarding the level of education of the participants and the frequency of extraction due to caries, the highest percentage was recorded in patients with secondary education (50%) and the lowest in pupils and students. The largest number of extractions was observed in people who only visited their general dentist when necessary. Within this group, as much as 59% of extraction was performed due to caries. The most commonly extracted teeth were lower third molars, while lower incisors were extracted the least. The most commonly extracted teeth due to caries were the lower first molars and the upper premolars. Conclusion: This study showed that caries was the main reason for permanent teeth extraction in Split, Croatia. This shows the importance of preventive procedures and regular checkups at the dentist in order to reduce the incidence of caries and consequent extractions.