prikaz prve stranice dokumenta PREVALENCE OF AUTOIMMUNE COMORBIDITIES IN NEWLY DIAGNOSED PEDIATRIC PATIENTS WITH TYPE 1 DIABETES
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master's thesis
PREVALENCE OF AUTOIMMUNE COMORBIDITIES IN NEWLY DIAGNOSED PEDIATRIC PATIENTS WITH TYPE 1 DIABETES
Split: University of Split, School of Medicine, 2021. urn:nbn:hr:171:684125
Rozić, Ella
University of Split
School of Medicine
Pediatrics

Cite this document

Rozić, E. (2021). PREVALENCE OF AUTOIMMUNE COMORBIDITIES IN NEWLY DIAGNOSED PEDIATRIC PATIENTS WITH TYPE 1 DIABETES (Master's thesis). Retrieved from https://urn.nsk.hr/urn:nbn:hr:171:684125

Rozić, Ella. "PREVALENCE OF AUTOIMMUNE COMORBIDITIES IN NEWLY DIAGNOSED PEDIATRIC PATIENTS WITH TYPE 1 DIABETES." Master's thesis, University of Split, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:171:684125

Rozić, Ella. "PREVALENCE OF AUTOIMMUNE COMORBIDITIES IN NEWLY DIAGNOSED PEDIATRIC PATIENTS WITH TYPE 1 DIABETES." Master's thesis, University of Split, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:171:684125

Rozić, E. (2021). 'PREVALENCE OF AUTOIMMUNE COMORBIDITIES IN NEWLY DIAGNOSED PEDIATRIC PATIENTS WITH TYPE 1 DIABETES', Master's thesis, University of Split, School of Medicine, accessed 21 May 2022, https://urn.nsk.hr/urn:nbn:hr:171:684125

Rozić E. PREVALENCE OF AUTOIMMUNE COMORBIDITIES IN NEWLY DIAGNOSED PEDIATRIC PATIENTS WITH TYPE 1 DIABETES [Master's thesis]. Split: University of Split, School of Medicine; 2021 [cited 2022 May 21] Available at: https://urn.nsk.hr/urn:nbn:hr:171:684125

E. Rozić, "PREVALENCE OF AUTOIMMUNE COMORBIDITIES IN NEWLY DIAGNOSED PEDIATRIC PATIENTS WITH TYPE 1 DIABETES", Master's thesis, University of Split, School of Medicine, Split, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:171:684125

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Metadata
TitlePREVALENCE OF AUTOIMMUNE COMORBIDITIES IN NEWLY DIAGNOSED PEDIATRIC PATIENTS WITH TYPE 1 DIABETES
Title (croatian)PREVALENCIJA AUTOIMUNOSNIH KOMORBIDITETA U NOVOOTKRIVENIH PEDIJATRIJSKIH BOLESNIKA SA ŠEĆERNOM BOLESTI TIPA 1
AuthorElla Rozić
MentorMarko Šimunović (mentor)
Committee memberMarino Vilović (predsjednik povjerenstva)
Committee memberJoško Božić (član povjerenstva)
Committee memberTina Tičinović Kurir (član povjerenstva)
GranterUniversity of Split
School of Medicine
(Pediatrics)
Split
Defense date and country2021-07-29, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pediatrics
Abstract
Objectives: The aim of this study was to determine levels of antibodies for celiac disease and autoimmune thyroiditis in newly diagnosed type 1 diabetes mellitus (T1DM) children and adolescents. Materials and methods: This study enrolled 110 newly T1DM pediatric patients in the period from January 2016 to December 2019. Evaluation included physical examination, medical history, anthropometric measurement and blood sample. Results: The cumulative prevalence of positive antibodies for celiac disease was 10.9 %, while prevalence of positive antibodies for autoimmune thyroiditis was 11.8 % in newly diagnosed patients with T1DM. Furthermore, subjects with additional autoimmune disease were statistically significantly older compared with subjects without additional autoimmune disease (11.3 ± 4.03 vs. 8.64 ± 4.44, P=0.004). Conclusion: This study has confirmed that new-onset T1DM in children and adolescents can present with non-islet, organ-specific autoantibodies. These results emphasize the importance of screening for celiac disease and autoimmune thyroiditis in newly diagnosed T1DM individuals.
Abstract (croatian)
Ciljevi: Cilj ovog istraživanja bio je utvrditi razine antitijela na celijakiju i autoimuni tireoiditis kod novootkrivene djece i adolescenata s šećernom bolesti tipa 1 (ŠBT1). Materijali i metode: U ovu je studiju uključeno 110 novootkrivenih pedijatrijskih bolesnika s ŠBT1 u razdoblju od siječnja 2016. do prosinca 2019. Procjena je uključivala fizikalni pregled, povijest bolesti, antropometrijsko mjerenje i uzorak krvi. Rezultati: Kumulativna prevalencija pozitivnih antitijela na celijakiju bila je 10,9%, dok je prevalencija pozitivnih antitijela na autoimuni tireoiditis bila 11,8% u novootkrivenih bolesnika s ŠBT1. Nadalje, ispitanici s dodatnom autoimunom bolešću bili su statistički značajno stariji u usporedbi s ispitanicima bez dodatne autoimune bolesti (11,3 ± 4,03 naspram 8,64 ± 4,44, P = 0,004). Zaključci: Ova je studija potvrdila da kod pacijenata s noovotkrivenom ŠBT1 mogu biti prisutan s auto-antitijelima koja nisu specifična za beta stanice, već su specifična za druge organske sustave. Navedeni rezultati ukazuju na važnost probira na celijakiju i autoimuni tiroiditis kod novootkrivenih bolesnika s ŠBT1.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:171:684125
Study programmeTitle: Medical Studies in English
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
RepositoryMEFST Repository
Created on2021-08-30 10:10:17