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master's thesis
Zadebljanje interventrikularnog septuma kao marker kardiomiopatije srca fetusa kod majki s gestacijskim dijabetesom
Split: University of Split, University Department of Health Studies, 2018. urn:nbn:hr:176:999934
Rakić, Marta
University of Split
University Department of Health Studies

Cite this document

Rakić, M. (2018). Zadebljanje interventrikularnog septuma kao marker kardiomiopatije srca fetusa kod majki s gestacijskim dijabetesom (Master's thesis). Retrieved from https://urn.nsk.hr/urn:nbn:hr:176:999934

Rakić, Marta. "Zadebljanje interventrikularnog septuma kao marker kardiomiopatije srca fetusa kod majki s gestacijskim dijabetesom." Master's thesis, University of Split, University Department of Health Studies, 2018. https://urn.nsk.hr/urn:nbn:hr:176:999934

Rakić, Marta. "Zadebljanje interventrikularnog septuma kao marker kardiomiopatije srca fetusa kod majki s gestacijskim dijabetesom." Master's thesis, University of Split, University Department of Health Studies, 2018. https://urn.nsk.hr/urn:nbn:hr:176:999934

Rakić, M. (2018). 'Zadebljanje interventrikularnog septuma kao marker kardiomiopatije srca fetusa kod majki s gestacijskim dijabetesom', Master's thesis, University of Split, University Department of Health Studies, accessed 29 May 2022, https://urn.nsk.hr/urn:nbn:hr:176:999934

Rakić M. Zadebljanje interventrikularnog septuma kao marker kardiomiopatije srca fetusa kod majki s gestacijskim dijabetesom [Master's thesis]. Split: University of Split, University Department of Health Studies; 2018 [cited 2022 May 29] Available at: https://urn.nsk.hr/urn:nbn:hr:176:999934

M. Rakić, "Zadebljanje interventrikularnog septuma kao marker kardiomiopatije srca fetusa kod majki s gestacijskim dijabetesom", Master's thesis, University of Split, University Department of Health Studies, Split, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:176:999934

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Metadata
TitleZadebljanje interventrikularnog septuma kao marker kardiomiopatije srca fetusa kod majki s gestacijskim dijabetesom
Title (english)INTERVENTRICULAR SEPTAL THICKNESS AS CARDIOMIOPATHY SIGN OF FETAL HEART IN MOTHERS WITH GESTATIONAL DIABETES MELLITUS
AuthorMarta Rakić
MentorFrane Mihanović (mentor)
Committee memberDiana Aranza (predsjednik povjerenstva)
Committee memberTatjana Matijaš (član povjerenstva)
Committee memberFrane Mihanović (član povjerenstva)
GranterUniversity of Split
University Department of Health Studies
Split
Defense date and country2018-09-06, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract
Ustroj istraživanja: kohortno istraživanje Mjesto istraživanja: Kardiološka ambulanta Dječje bolnice Srebrnjak, Zagreb Sudionici: Trudnice kojima je u trudnoći dijagnosticiran gestacijski dijabetes melitus (GDM) i kojima je zbog toga indicirana fetalna ehokardiografija od siječnja 2017. do ožujka 2018. godine, a rodile su od svibnja 2017. do travnja 2018. godine. Glavne mjere ishoda: Izmjerene debljine IVS-a, mjerene u M-modu. Podatci su prikupljeni mjerenjem, za vrijeme ultrazvučnog pregleda fetalne ehokardiografije. Debljina IVS-a mjerena je prenatalno i postnatalno, ultrazvučnim pregledom u prvim mjesecima života. Kriterij za hipertrofiju IVS-a je vrijednost Z-skora >1.65. Rezultati: U Kardiološkoj ambulanti Dječje bolnice Srebrnjak fetalnom ehokardiografijom pregledano je 320 trudnica s dijagnozom GDM-a, što iznosi oko 25% svih pregleda fetalne ehokardiografije. U istraživanju su analizirani podatci i mjerenja 42 trudnice i njihovih fetusa/djece. Trudnice s GDM-om upućivane su na fetalnu ehokardiografiju u ranijoj gestacijskog dobi nego trudnice iz kontrolne skupine (t=2.676, p=0.011). Učestalost hipertrofije IVS-a na prvom pregledu u skupini trudnica s GDM-om bila je granično veća (p=0.112), dok na kontrolnom pregledu razlika nije bila statistički značajna (p=0.404). Debljine IVS-a izmjerene u Mmodu i evaluirane Z-skorom na postnatalnom pregledu statistički su značajno veće u skupini trudnica s GDM-om (Mmode t=2.556, p=0.015; Z-skore t=2.708, p=0.010). Učestalost hipertrofije IVS-a na postnatalnom pregledu u skupini trudnica s GDM-om je statistički značajno veća u odnosu na kontrolnu skupinu (p=0.010) uz značajno povećanu šansu za hipertrofiju (OR=12.3, 95% CI 1.3-118.1). Zaključak: Debljina IVS-a mjerena prenatalno bila je granično povećana kod fetusa čijim je majkama u trudnoći dijagnosticiran GDM u odnosu na kontrolnu skupinu. Hipertrofija IVS-a na postnatalnom pregledu utvrđena je u istoj skupini s još većom učestalosti, unatoč praćenju i nastojanjima da se postigne dobra razina glikemije tijekom trudnoće.
Abstract (english)
Study design: cohort study Study location: Cardiology clinic, Srebrnjak Children's Hospital, Zagreb Participants: Study included pregnant women who have been diagnosed gestational diabetes mellitus (GDM) and were examined by fetal echocardiography form January 2017. to March 2018, and gave birth from May 2018. to April 2018. Main outcome measures: In Cardiology clinic of Children's Hospital Srebrnjak, we examined 320 pregnant women with GDM, accounting about 25% of all fetal echocardiography examinations. The study analyzed data and measurements of 42 pregnant women and their fetuses/children. Pregnant women with GDM referred to fetal echocardiography at an earlier gestational age than pregnant women in the control group (t=2.676, p=0.011). The criterion for IVS hypertrophy at the first examination in the GDM pregnant group showed a marginal statistical value (χ2 = 3.231, P = 0.072), while the difference in control group exists, but it is not statistically significant (χ2=0.673, p=0.412). The IVS thickness measured in Mmode and evaluated with Z-score on postnatal examination was increased in the GDM pregnant group (Mmode t=2.556, p=0.015; Z-score t=2.708, p=0.010). The criterion for IVS hypertrophy on postnatal examination in the GDM pregnancies showed statistically significant difference in corelation to the control group (χ2=6.929, p=0.008). The incidence of IVS hypertrophy on postnatal examinationin the GDM pregnant group was statistically higher in corelation to the control group (p=0.010), with significantly increased possibility of hypertrophy (OR=12.3, 95% CI 1.3-118.1). Conclusion: The IVS thickness measured in fetuses from mothers with GDM was increased in corelation with control group, but with a marginal statictical value. IVS hypertrophy was found in the same gruop, with an even greater incidence on a postnatal examination in spite efforts to achieve good glycaemic control during pregnancy.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:176:999934
Study programmeTitle: Radiologic Technology (university/graduate)
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra radiološke tehnologije (magistar/magistra radiološke tehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
RepositoryUniversity Department for Health Studies Repository
Created on2020-05-13 07:36:40