Aim: The aim of this study was to collect sociodemografic data from second and third year undregraduate nursing students from University of of health studies in Split; determine possible prejudices toward patients suffering from schizophrenia and to establishe the difference between their attitudes towards them. Material and methods: The study was conducted in May 2016. on 60 nursing students (30 of them were sedond year and 30 were third year) using two questionnares. The first questionnaire consisted of 5 questions regarding sociodemographic data, and the second, consisted of 14 questions, refered to students opinion toward schizophrenic patients. The participants were nursing students from the University of health studies in Split. The questionnare was taken from proffesor.med.techn. Matea Šarić. The survey was filled voluntarily and anonymously. Answers regarding the claims in the survey were recorded using Likert scalefrom 1 to 5, whereby 1 means that the participant strongly disagrees, 2 means that the participant disagrees, 3 the participant neither agrees nor disagrees, 4 the participant agrees and 5 means the participant strongly agrees. The data collected from the surway was entered into a Microsoft Excel spreadsheet according to a pre-prepared chart of accounts. For processing, descriptive statistics and χ² test were used. Results: The results Indicated that a higher persentage of female gender was represented among second year students (76%) and 83% among third year students. The age category of 19 to 25 years was highly represented with 73% of second year students and 63% of third year students, meaning that most of our participants enrolled straight after their highschool education (60% second year and 47% third year). The results of the second part of the study contains opinions regarding schizophrenic patients. Statistically, significant differences between second and third year students was noted regarding the opinions that Schizophrenic is dangerous to himself (second year students have shared opinions (43.3%) they either can't make up their mind or they agree, while third year students also can not make up their mind, 43.3% strongly disagree versus strongly agree), Schizophrenic patient is incapable of independent decision-making,life and earning (third year students completely disagree (60%) while second year students equally state they neither agree nor disagree or they completely agree (36.6%). Third year students state that they disagree (70%) with third statement: Patients with schizophrenia are dangerous for other people, they are agressive, while second year students disagree with the statement in 20%. Also second year students (46.6%) state that they agree with the statement Schizophrenia is a incurable disease, while 60% of the third year students agree. Schizophrenic patient is incapable of living alone, 63.3% of third year students strongly disagree while second year studente have divided opinions, 33.3% either strongly disagree or they neither agrre nor disagree. I would rather suffer from a cardiovascular disease then mental disease, 46.6% of second year students can't decide, while 66.6% of third year students completely agree. Conclusion: We can conclude that there are differences in opinion between second and third year students toward schizophrenic patients. We can also conclude there is a significant difference after completing the course in health care of psychiatric patients , and a change in attitude and thinking concerning schizophrenic patients.